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CRISPR safety switch can make cells self-destruct if they go rogue

Health 21 February 2020 By Michael Le Page A safety switch may pave the way towards controlled use of gene drives to control mosquitoesJoao Paulo Burini/GettyA genetic tweak can make cells self-destruct in the presence of CRISPR and could be used to shut down cell therapies if they go rogue. CRISPR gene editing can be…



Health



21 February 2020

By Michael Le Page

A safety switch may pave the way towards controlled use of gene drives to control mosquitoes

A safety switch may pave the way towards controlled use of gene drives to control mosquitoes

Joao Paulo Burini/Getty

A genetic tweak can make cells self-destruct in the presence of CRISPR and could be used to shut down cell therapies if they go rogue.

CRISPR gene editing can be used to efficiently and easily introduce changes to the DNA of living cells. It is a useful technique, but it would be handy to be able to make some cells CRISPR-resistant. For example, there is interest in storing information in DNA inside cells, and rendering some of these uneditable by …

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