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Experimental diabetes device works by killing gut cells with hot water

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By Clare Wilson Illustration of the device used in the Revita procedureFractylA bizarre diabetes treatment seems to destroy cells lining the gut to change people’s hormonal response to food. The technique involves putting a tube down someone’s throat and into the first part of their small intestine, called the duodenum, while they are sedated. Known as Revita,…

By Clare Wilson

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Illustration of the device used in the Revita procedure

Fractyl

A bizarre diabetes treatment seems to destroy cells lining the gut to change people’s hormonal response to food.

The technique involves putting a tube down someone’s throat and into the first part of their small intestine, called the duodenum, while they are sedated. Known as Revita, the procedure uses water heated to 75°C to kill the outermost layer of cells.

People with type 2 diabetes, which is linked with being overweight, often have overgrowth of the cells lining the duodenum. This may result from years of unhealthy eating, …

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